Mind Blowing
Although a little bit similar to a lot of the other lists, this list tends to be more science oriented. Many of the books are non-fiction and science or history related.
The Tipping Point by Gladwell
How To Win Friends and Influence People by Carnegie
Freakonomics by Dubner
The Omnivore's Dilemma by Pollan
Lies My Teacher Told Me by Loewen
In Defense of Food by Pollan
Shantaram by Roberts
Zen and the Art of Motorcycle Maintenance by Pirsig
The Man Who Mistook His Wife For A Hat by Sacks
Godel, Escher, Bach by Hofstadter
A Brief History of Time by Hawking
Collapse by Diamond
The Selfish Gene by Dawkins
The Creature from Jekyll Island by Griffin
Guns, Germs, and Steel by Diamond
The Demon-Haunted World by Sagan
Surely You're Joking, Mr. Feynman! by Feynman
A Short History of Nearly Everything by Bryson
The Autobiography of Malcolm X by X
Into Thin Air by Krakauer
The Botany of Desire by Pollan
A People's History of the United States by Zinn
Band of Brothers by Ambrose
Orientalism by Said